Selection.ClearCharacterDirectFormatting (Word)
Removes character formatting (formatting that has been applied manually using the buttons on the ribbon or through the dialog boxes) from the selected text.
This method does not remove character formatting that has been applied by using a character style. To remove character formatting that the user has applied by using character styles, use the ClearCharacterStyle method. To remove all character formatting, regardless of whether the user has applied it by using character styles or manually through the formatting features in Microsoft Word, use the ClearCharacterAllFormatting method.
Selection.ClearCharacterDirectFormatting